Immunosuppression and Neuroinflammation in Stroke Pathobiology
نویسندگان
چکیده
منابع مشابه
Stroke-induced immunosuppression and poststroke infection
Infections occur commonly after stroke and are strongly associated with an unfavourable functional outcome of these patients. Approaches for effective management of poststroke infection remain scarce, presenting an urgent need for preventive anti-infection strategies for patients who have suffered a stroke. Emerging evidence indicates that stroke impairs systemic immune responses and increases ...
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Inflammation has a pivotal role in the pathogenesis of ischemic stroke, and recent studies posit that inflammation acts as a double-edged sword, not only detrimentally augmenting secondary injury, but also potentially promoting recovery. An initial event of inflammation in ischemic stroke is the activation of microglia, leading to production of both pro- and anti-inflammatory mediators acting t...
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ژورنال
عنوان ژورنال: Experimental Neurobiology
سال: 2021
ISSN: 1226-2560,2093-8144
DOI: 10.5607/en20033